| Contents |
| Significant Research Papers, Medical Journals - updated 02 Jul 2011 |
| Scanning Protocols, Papers and Results |
| Slideshows from Conference Presentations |
| Related Papers - updated 02 Feb 2011 |
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Significant Research Papers, Medical Journals
| 2011 |
New!
Brain, 2011 Jul;134(Pt 7)
Haider L, Fischer M, Frischer J, Bauer J, Höftberger R, Botond G, Esterbauer H, Binder C, Witztum J and Lassmann H
| Download PDF: |
Oxidative damage in multiple sclerosis lesions |
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J Neurol Neurosurg Psychiatry, 2011 Feb, published online in advance of the print journal.
Mayer C, Pfeilschifter W, Lorenz M, Nedelmann M,
Bechmann I, Steinmetz H, Ziemann U
| Paper critical of link between CCSVI and MS |
| Download PDF: |
The perfect crime? CCSVI not leaving a trace in MS |
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Annals of Neurology 2011 January, Volume 69, Issue 1, pages 90–99, January 2011
Baracchini C, Perini P, Calabrese M, Causin F, Rinaldi F, Gallo P
| Paper critical of link between CCSVI and MS |
| Download PDF: |
No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset |
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| 2010 |
Phlebology 2010 DecemberVolume 25, 6, p286-295
Ludyga T, Kazibudzki M, Simka M, Hartel M, Wierad M, Piegza J, Latacz P,
Sedlak L, Tochowicz M
| Download PDF: |
Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe? |
| View Reportage from ECTRIMS | MS Researchers Share Progress at Annual ECTRIMS Conference NMSS CCSVI Science - The Latest Results and Their Relevance Daily Strength |
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Annals of Neurology 2010 August
Sundström P, Wåhlin A, Ambarki K, Birgander R, Eklund A, Malm J
| Paper critical of link between CCSVI and MS |
| Download PDF: | Venous and cerebrospinal fluid flow in multiple sclerosis: A case-control study |
| N.B. | Scans for this study were carried out using MRI and only tested patients with one type of Multiple Sclerosis |
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Annals of Neurology 2010 July
Doepp F, Paul F, Valdueza JM, Schmierer K, Schreiber SJ
| Paper critical of link between CCSVI and MS |
| Download PDF: | No cerebro-cervical venous congestion in patients with multiple sclerosis |
| N.B. | This study primarily used ultrasound scans and followed a different protocol to Professor Zamboni |
| View as HTML |
Professor Zamboni's response in Annals of Neurology |
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International Angiology, 2010 Apr; 29(2), pp109-14
Simka M, Kostecki J, Zaniewski M, Majewski E, and Hartel M:
| Download PDF: | Extracranial Doppler sonographic criteria of chronic cerebrospinal venous insufficiency in the patients with multiple sclerosis |
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International Angiology, 2010 Apr; 29(2), pp115-20
Al-Omari MH, and Rousan LA:
| Download PDF: | Internal jugular vein morphology and hemodynamics in patients with multiple sclerosis |
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International Angiology, 2010 Apr; 29(2), pp121-6
Menegatti E, Genova V, Tessari M, Malagoni AM, Bartolomei I, Zuolo M, Galeotti R, Salvi F, and Zamboni P:
| Download PDF: | The reproducibility of colour Doppler in chronic cerebrospinal venous insufficiency associated with multiple sclerosis |
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International Angiology, 2010 Apr; 29(2), pp127-39
| Hojnacki D, Zamboni P, Lopez-Soriano A, Galleotti R, Menegatti E, Weinstock-Guttman B, Schirda C, Magnano C, Malagoni AM, Kennedy C, Bartolomei I, Salvi F, and Zivadinov R: |
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International Angiology, 2010 Apr; 29(2), pp140-8
| Zamboni P, Menegatti E, Weinstock-Guttman B, Schirda C, Cox JL, Malagoni AM, Hojnacki D, Kennedy C, Carl E, Dwyer MG, Bergsland N, Galeotti R, Hussein S, Bartolomei I, Salvi F, Ramanathan M, and Zivadinov R: |
Download PDF: |
CSF dynamics and brain volume in multiple sclerosis are associated with extracranial venous flow anomalies: a pilot study |
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International Angiology, 2010 Apr; 29(2), pp149-57
Haacke EM, Garbern J, Miao Y, Habib C, and Liu M:
| Download PDF: | Iron stores and cerebral veins in MS studied by susceptibility weighted imaging |
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International Angiology, 2010 Apr; 29(2), pp158-75
| Zivadinov R, Schirda C, Dwyer MG, Haacke ME, Weinstock-Guttman B, Menegatti E, Heininen-Brown M, Magnano C, Malagoni AM, Wack DS, Hojnacki D, Kennedy C, Carl E, Bergsland N, Hussein S, Poloni G, Bartolomei I, Salvi F, and Zamboni P: |
Download PDF: |
Chronic cerebrospinal venous insufficiency and iron deposition on susceptibility-weighted imaging in patients with multiple sclerosis: a pilot case-control study (from Fondazione Hilarescere) |
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International Angiology, 2010 Apr; 29(2), pp176-82
Malagoni AM, Galeotti R, Menegatti E, Manfredini F, Basaglia N, Salvi F, and Zamboni P:
| Download PDF: | Is chronic fatigue the symptom of venous insufficiency associated with multiple sclerosis? A longitudinal pilot study |
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International Angiology, 2010 Apr; 29(2), pp183-8
Bartolomei I, Salvi F, Galeotti R, Salviato E, Alcanterini M, Menegatti E, Mascalchi M, and Zamboni P:
| Download PDF: | Hemodynamic patterns of chronic cerebrospinal venous insufficiency in multiple sclerosis. Correlation with symptoms at onset and clinical course |
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| 2009 |
Journal of Cerebral Blood Flow & Metabolism (2009) 29, 1867–1878 New!
Ajay Vikram Singh and Paolo Zamboni
| Download PDF: | Anomalous venous blood flow and iron deposition in multiple sclerosis |
Functional Neurology 2009, 24(3): pp 133-138
Dr Paolo Zamboni et al.
View as HTML
| Download PDF: | The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamic |
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International Angiology, 2009 Dec; ;28(6):434-51. Montecarlo September 4th 2009
Lee BB, Bergan J, Gloviczki P, Laredo J, Loose DA, Mattassi R, Parsi K, Villavicencio JL, and Zamboni P:
| Download PDF: | Diagnosis and treatment of venous malformations: Consensus Document of the International Union of Phlebology (IUP)-2009 |
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Journal of Vascular Surgery, Vol 50, Issue 6, pp 1348-1358
2009, December
P Zamboni, R Galeotti, E Menegatti, et al.
| Download PDF: | A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency |
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31st International Symposium, Charing Cross: Controversies, Challenges, Consensus;
2009, April 06
Vascular and Endovascular Controversies Update, pp. 71-79
Dr. Paolo Zamboni et al. (from Fondazione Hilarescere)
| Download PDF: | Rationale and preliminary results of endovascular treatment of multiple sclerosis, the liberation procedure (from Fondazione Hilarescere) |
| View as HTML | Prof. Zamboni's Presentation: Video of Slides |
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Current Neurovascular Research 2009, Vol 6, 132-9
2009, May
Dr. Marian Simka
| Download PDF: | Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during multiple sclerosis |
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J Neurol Neurosurg Psychiatry 2009 80: 392-399
Epub2008, December 05
P Zamboni, R Galeotti, E Menegatti, et al.
View as HTML
| Download PDF: | Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis |
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Journal of the Neurological Sciences 282 (2009) 21–27
2009, January
Paolo Zamboni et al.
| Download PDF: | The value of cerebral Doppler venous haemodynamics in the assessment of multiple sclerosis |
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Current Neurovascular Research 2009 Vol 6, 204-212
2009, September 02
P Zamboni, R Galeotti, E Menegatti, et al.
| Download PDF: | Venous Collateral Circulation of the Extracranial Cerebrospinal Outflow Routes |
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| 2008 |
Current Neurovascular Research, 2008, 5, pp260-265
Dr. Paolo Zamboni and Erica Menegatti
| Download PDF: | Doppler Haemodynamics of Cerebral Venous Return |
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| 2007 |
Current Neurovascular Research, 2007, 4, pp252-258
Dr. Paolo Zamboni and Team
| Download PDF: | Intracranial Venous Haemodynamics in Multiple Sclerosis |
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Phlebology Vol 22 No. 6 2007, pp249-252
Special Issue: Venous malformations
B B Lee, J Laredo, T S Lee-, S Huh- and R Neville
| Download PDF: | Terminology and classification of congenital vascular malformations |
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| 2006 |
Journal of the Royal Society of Medicine
JRSM, Vol 99, No 11, pp589-593
2006, July 01, Dr. Paolo Zamboni
View as HTML
| Download PDF: | The big Idea: Iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis |
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Scanning Protocols, Papers and Results
| 2010 |
| 2010, February 04, Buffalo Neuroimaging Analysis Centre, Director Dr. Robert Zivadinov, MD, PhD |
| Download PDF: | BNAC CCSVI Newsletter, Volume 1, Issue 1 |
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| 2009 |

2009, Oct 29, E. Mark Haacke, PhD, Wayne State University
View as HTML
| Download PDF: | Multiple Sclerosis (MS) Protocol Training |
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Journal of Magnetic Resonance Imaging 2009 Mar;29(3):537-44.
Haacke EM, et al.
| Download PDF: | Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging |
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2009, Dr. Marian Simka, Naleczow, Poland
| Download PDF: | The many sonographic faces of the chronic cerebrospinal venous insufficiency: How to perform doppler examination in a multiple sclerosis patient |
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Slideshows from Conference Presentations
| 2010 |
| 2010, February 7th Presentation by: Dr. E. Mark Haacke, McMaster Institute, Wayne State University at Chronic Cerebral Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Scientific Workshop, Canada - Hamilton, St. Joseph's Hospital |
| Download PDF: | Is the Basic Etiology of Multiple Sclerosis Vascular in Origin? |
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| 2010, February 7th Presentation by: Prof. Michael D. Dake, Dept. of Cardiothoracic Surgery, Stanford University at Chronic Cerebral Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Scientific Workshop Canada - Hamilton, St. Joseph's Hospital |
(from www.ms-mri.com)
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| 2010, February 7th Presentation by: Dr. Marian Simka, Katowice, Poland at Chronic Cerebral Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Scientific Workshop Canada - Hamilton, St. Joseph's Hospital |
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| 2010, February 7th Presentation by: Dr. Robert Zivadinov, University of Buffalo at Chronic Cerebral Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Scientific Workshop Canada - Hamilton, St. Joseph's Hospital |
Download PDF: CCSVI and MRI Outcomes in MS
(from www.ms-mri.com)
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| 2010, February 7th Presentation by: Dr. M Al-Omari and Dr. L. Rousan, Jordan University of Science and Technology at Chronic Cerebral Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Scientific Workshop Canada - Hamilton, St. Joseph's Hospital |
Download PDF: CCSVI: Evidence from Jordanian Experience
(from www.ms-mri.com)
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| 2010, February 7th Presentation by: Prof. Paolo Zamboni, University of Ferrara, Italy at Chronic Cerebral Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Scientific Workshop Canada - Hamilton, St. Joseph's Hospital |
Download PDF: Presentation by Professor Zamboni
(from www.ms-mri.com) __________________________________________________________________________________________________
| 2009 |
| 2009, October 1st Presentation by: Dr. E. Mark Haacke, McMaster Institute, Wayne State University, at MRI Club |
| Download PDF: | Multiple Sclerosis with Iron and Chronic Cerebral Spinal Vascular Insufficiency (CCSVI) (from www.ms-mri.com) |
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| 2009, 31 Aug - 4 Sept, Presentation by: Dr. Marian Simka, Department of Angiology, Pszczyna, Poland, XVI World Congress of the Union Internationale de Phlébologie, Monaco |
| Download PDF: | Chronic cerebrospinal venous insufficiency and multiple sclerosis: theoretical and practical issues |
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| 2007 |
2007, April 14-17
London, Charing Cross Symposium
Presentation by Prof Paolo Zamboni
| Download PDF: | Cerebro spinal venous outflow impairment and multiple sclerosis: A new challenge? |
Related papers
| 2011 |
2011, February, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: |
A New Disease Model for MS |
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2011, February 02, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: |
What the MS Society of Canada Does Not Want You to Know About their Finances |
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| 2010 |
2010, December 23, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: | The Sad, Sad State of CCSVI Research in Alberta |
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2010, September 10, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: | An In-Depth Analysis of the "Summary Report - CIHR and MS Society of Canada Joint Invitational Meeting on Multiple Sclerosis Research |
| Download PDF: | Executive Summary |
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2010, September 03, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: | Up Close and Personal with CCSVI |
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2010, August 06, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: | An Open Letter to the Honourable Gene Zwozdesky, Alberta Minister of Health Regarding the August 6, 2010, Alberta Health Services Report on MS and CCSVI |
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Endovascular Today, 2010, July: 41-46, Cover Story
Salvatore J.A. Sclafani, MD,
with commentary by Michael D. Dake, MD, and Barry T. Katzen, MD:
| Download PDF: | Chronic Cerebrospinal Venous Insufficiency - A new paradigm and therapy for multiple sclerosis. |
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2010, July, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: | New Studies Show the MS Drugs Don't Slow Progression |
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2010, May, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
Download PDF: The Liberation War
__________________________________________________________________________________________________2010, May, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
Download PDF: Submission to Parliamentary Subcommittee on Neurological Health
__________________________________________________________________________________________________2010, April, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
| Download PDF: | Why Direct-MS Advocates that Persons with MS Should Get Tested and Treated for MS As Soon As Possible |
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2010, April, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
View as HTML
Download PDF: CCSVI – Some More Thoughts
__________________________________________________________________________________________________2010, March, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
View as HTML
| Download PDF: | New Data on CCSVI and Vitamin D Underscore the Need for Taking Action |
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2010, Mark Lillywhite, Australia
Download PDF: CCSVI and Multiple Sclerosis - a white paper__________________________________________________________________________________________________
| 2009 |
2009, December, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
View as HTML
| Download PDF: | Hope and Elation - Frustration and Anger – Fear and Loathing: The Contrasting Emotional Responses to the Revolutionary Discoveries in MS Made by Dr Zamboni |
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2009, Ashton Embry, Ph.D., Calgary, Canada. Direct-MS (www.direct-ms.org)
View as HTML
Download PDF: CCSVI and Multiple Sclerosis: Integrating New Data to Help Guide Actions
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2009, September 08
Press Release: Fondazione Hilarescere
Download PDF: Venous function and Multiple Sclerosis

